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Article

Antigenic and/or phase variation of PorA protein in non-subtypable Neisseria meningitidis strains isolated in Spain.

Journal of medical microbiology - 1 Jun 2004

Alcalá Belen, Salcedo Celia, Arreaza Luisa, Abad Raquel, Enríquez Rocio, De La Fuente Laura, Uría Maria Jose, Vázquez Julio A

Abstract excerpt

The PorA protein is a potential candidate as a vaccine component against meningococcal disease. However, this protein experiences antigenic variation and is subject to phase variations to evade immune selective pressure. In this study, the mechanisms responsible for altered expression of the PorA protein were analysed in 50 non-subtypable strains isolated from patients with meningococcal disease in Spain. The...

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Share to Antigenic Variation
Share to Meningitis, Meningococcal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Neisseria meningitidis

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 15150331
DOI: 10.1099/jmm.0.05517-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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