Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Herp in the endoplasmic reticulum stress response.

Genes to cells : devoted to molecular & cellular mechanisms - 1 May 2004

Hori Osamu, Ichinoda Fusae, Yamaguchi Atsushi, Tamatani Takashi, Taniguchi Manabu, Koyama Yoshihisa, Katayama Taiichi, Tohyama Masaya, Stern David M, Ozawa Kentaro, Kitao Yasuko, Ogawa Satoshi

Abstract excerpt

Application of differential display to cultured rat astrocytes allowed cloning of Herp cDNA. Although Herp was strongly induced by endoplasmic reticulum (ER) stress, it decayed rapidly consequent to proteasome-mediated degradation. To investigate the role of this molecule in terms of the stress response, Herp knockout cells were developed using F9 embryonic carcinoma cells. F9 Herp null cells were more vulnerable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Hypoxia
Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Astrocytes

Share to Cell Death

Share to Endoplasmic Reticulum

Share to Gene Deletion

Share to Microscopy, Electron, Transmission

Share to Rats, Wistar

Source

Identifiers

PMID: 15147274
DOI: 10.1111/j.1356-9597.2004.00735.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Herp in the endoplasmic reticulum stress response.PMID 15147274Read ↗

The endoplasmic reticulum (ER)-associated degradation system regulates aggregation and degradation of mutant neuroserpin.Semantic proximity Read ↗

The ER Stress Surveillance (ERSU) pathway regulates daughter cell ER protein aggregate inheritanceSemantic proximity Read ↗

Lectin OS-9 delivers mutant neuroserpin to endoplasmic reticulum associated degradation in familial encephalopathy with neuroserpin inclusion bodies.Semantic proximity Read ↗

Targeted protein destabilization reveals an estrogen-mediated ER stress responseSemantic proximity Read ↗

Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice.Semantic proximity Read ↗

HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stressSemantic proximity Read ↗

SELENOT–Knockdown Leads to Reducing the Expression of Key Enzymes of ERAD–System in Cancer Cells Under ER–StressSemantic proximity Read ↗

CRELD2 is a novel endoplasmic reticulum stress-inducible geneSemantic proximity Read ↗

The KDEL receptor modulates the endoplasmic reticulum stress response through mitogen-activated protein kinase signaling cascades.Semantic proximity Read ↗

PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation.Semantic proximity Read ↗

Characterization of the sterol and phosphatidylinositol 4-phosphate binding properties of Golgi-associated OSBP-related protein 9 (ORP9).Semantic proximity Read ↗

Endoplasmic reticulum protein 29 (ERp29): An emerging role in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.