Article
The bacA gene of Escherichia coli encodes an undecaprenyl pyrophosphate phosphatase activity.
The Journal of biological chemistry - 16 Jul 2004
El Ghachi Meriem, Bouhss Ahmed, Blanot Didier, Mengin-Lecreulx Dominique
Abstract excerpt
The bacA gene, the overexpression of which results in bacitracin resistance, was inactivated and shown to be non-essential for growth of Escherichia coli. It was proposed earlier that the bacA gene product may confer resistance to the antibiotic by phosphorylation of undecaprenol (Cain, B. D., Norton, P. J., Eubanks, W., Nick, H. S., and Allen, C. M. (1983) J. Bacteriol. 175, 3784-3789). In the present work, this...
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