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Article

Whole genome sequencing analysis of multidrug-resistant tuberculosis in Singapore, 2006-2018.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2021

Chee Cynthia B E, Lim Leo K Y, Ong Rick T H, Sng Li Hwei, Hsu Li Yang, Lee Vernon J M, Wang Yee Tang

Abstract excerpt

There were 290 multidrug-resistant (MDR)-TB cases diagnosed in Singapore from 2006 to 2018. Eighty-one percent were foreign-born. Spoligotyping and MIRU-VNTR methods identified 108 patients in 24 clusters. The Beijing spoligotype accounted for 22 clusters. Whole genome sequencing (WGS) analysis reduced the number of clustered patients and clusters to 43 and nine respectively. One MIRU cluster was redefined into...

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PMID: 33190171
DOI: 10.1007/s10096-020-04100-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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