Article
An amino-terminal domain of Enterococcus faecalis aggregation substance is required for aggregation, bacterial internalization by epithelial cells and binding to lipoteichoic acid.
Molecular microbiology - 1 May 2004
Waters Christopher M, Hirt Helmut, McCormick John K, Schlievert Patrick M, Wells Carol L, Dunny G M
Abstract excerpt
Aggregation substance (AS), a plasmid-encoded surface protein of Enterococcus faecalis, plays important roles in virulence and antibiotic resistance transfer. Previous studies have suggested that AS-mediated aggregation of enterococcal cells could involve the binding of this protein to cell wall lipoteichoic acid (LTA). Here, a method to purify an undegraded form of Asc10, the AS of the plasmid pCF10, is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.