Article
Acceleration of Enterococcus faecalis biofilm formation by aggregation substance expression in an ex vivo model of cardiac valve colonization.
PloS one - 30 Dec 2010
Chuang-Smith Olivia N, Wells Carol L, Henry-Stanley Michelle J, Dunny Gary M
Abstract excerpt
Infectious endocarditis involves formation of a microbial biofilm in vivo. Enterococcus faecalis Aggregation Substance (Asc10) protein enhances the severity of experimental endocarditis, where it has been implicated in formation of large vegetations and in microbial persistence during infection....
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