Article
Prediction of amino acid pairs sensitive to mutations in the spike protein from SARS related coronavirus.
Peptides - 1 Dec 2003
Wu Guang, Yan Shaomin
Abstract excerpt
In this study, we analyzed the amino acid pairs affected by mutations in two spike proteins from human coronavirus strains 229E and OC43 by means of random analysis in order to gain some insight into the possible mutations in the spike protein from SARS-CoV. The results demonstrate that the randomly unpredictable amino acid pairs are more sensitive to the mutations. The larger is the difference between actual and...
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