Article
Mutation patterns in human alpha-galactosidase A.
Molecular diversity - 1 Feb 2010
Yan Shaomin, Wu Guang
Abstract excerpt
A way to study the mutation pattern is to convert a 20-letter protein sequence into a scalar protein sequence, because the 20-letter protein sequence is neither vector nor scalar while a promising way to study patterns is in numerical domain. In this study, we use the amino-acid pair predictability to convert alpha-galactosidase A with its 137 mutations into scalar sequences, and analyse which amino-acid pairs...
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