Article
Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified.
Biological psychiatry - 15 May 2004
Addington Anjené M, Gornick Michele, Sporn Alexandra L, Gogtay Nitin, Greenstein Deanna, Lenane Marge, Gochman Peter, Baker Natalie, Balkissoon Rishi, Vakkalanka Radha Krishna, Weinberger Daniel R, Straub Richard E, Rapoport Judith L
Abstract excerpt
BACKGROUND: Childhood-onset schizophrenia (COS), defined as onset of psychotic symptoms by age 12 years, is a rare and severe form of the disorder that seems to be clinically and neurobiologically continuous with the adult disorder. METHODS: We studied a rare cohort consisting of 98 probands; 71 of these probands received a DSM-defined diagnosis of schizophrenia, and the remaining 27 were diagnosed as psychosis...
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