Article
Rapid detection and differentiation method of VanA, VanB and VanC phenotypes in vancomycin-resistant enterococci.
International journal of antimicrobial agents - 1 May 2004
Hanaki Hideaki, Yamaguchi Yoshio, Nomura Syuichi, Nagayama Ariaki, Sunakawa Keisuke
Abstract excerpt
We developed a simple method that can replace the polymerase chain reaction (PCR) to distinguish between vancomycin-resistant enterococci (VRE) with the vanA, vanB and vanC genes. The method is based on induction of teicoplanin resistance by vancomycin in vanB-VRE, while the two compounds have a synergistic effect in vanC-VRE. In addition, vanA-VRE shows resistance to both vancomycin and teicoplanin, and both the...
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