Article
Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with the development of lupus nephritis.
Lupus - 1 Jan 2004
Lee Y H, Kim H J, Rho Y H, Choi S J, Ji J D, Song G G
Abstract excerpt
The objective was to investigate whether the functional polymorphism of intron 4 in the endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to systemic lupus erythematosus (SLE) and its clinical features. The 27-bp repeat polymorphism in intron 4 of the eNOS gene was determined by polymerase chain reaction in 88 SLE patients and 95 healthy control subjects. Clinical manifestations were...
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