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Article

Characterization of a new type HPV16 E7 variant isolated from cervical cancer highest incidence area in Hubei Province of China.

Eksperimental'naia onkologiia - 1 Mar 2004

Li Hui, Zhao Min, Qiu Xiaoping, Ding Xiaohua, Tan Yun, Wu Xinxing

Abstract excerpt

AIM: To investigate the variation and biological properties of HPV16 E7 isolated from cervical cancer biopsy samples from highest incidence area in HuBei province of China. METHODS: HVP16 E7 sequences isolated from the cervical cancer biopsies of 10 local patients were amplified, sequenced and compared with prototype E7 gene. Then the variant gene was cloned into different vectors to study the antigenicity,...

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PMID: 15112580

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