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Article

Failure to detect enterovirus in the spinal cord of ALS patients using a sensitive RT-PCR method

27 Apr 2004

Abstract excerpt

OBJECTIVE: To assess the association of enteroviruses (EV) with ALS by applying a sensitive seminested reverse transcription (RT) PCR protocol to the detection of enteroviral RNA in a blinded set of archived tissues from ALS and control cases. METHODS: The specimen set consisted of 24 frozen spinal cord samples from ALS cases, 17 frozen spinal cord samples from negative control (non-ALS) cases, and 5 frozen...

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PMID: 15111676
DOI: 10.1212/01.wnl.0000123258.86752.51

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