Article
Mutations in the hMLH1 gene in Slovenian patients with gastric carcinoma.
Clinical genetics - 1 May 2004
Hudler P, Vouk K, Voulk K, Liovic M, Repse S, Juvan R, Komel R
Abstract excerpt
Alterations of multiple oncogenes and tumor suppressor genes, together with genetic instability, are responsible for carcinogenesis in gastric cancer. The microsatellite mutator phenotype is the cause of many somatic frameshift and point mutations in non-coding repetitive sequences and in coding...
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