Article
Non-invasive metabolic imaging of brain tumours in the era of precision medicine.
Nature reviews. Clinical oncology - 1 Dec 2016
Kim Michelle M, Parolia Abhijit, Dunphy Mark P, Venneti Sriram
Abstract excerpt
The revolution in cancer genomics has uncovered a variety of clinically relevant mutations in primary brain tumours, creating an urgent need to develop non-invasive imaging biomarkers to assess and integrate this genetic information into the clinical management of patients. Metabolic reprogramming is a central hallmark of cancer, including brain tumours; indeed, many of the molecular pathways implicated in the...
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