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Article

The fission yeast ptr1+ gene involved in nuclear mRNA export encodes a putative ubiquitin ligase.

Biochemical and biophysical research communications - 14 May 2004

Andoh Tomoko, Azad Abul Kalam, Shigematsu Asako, Ohshima Yasumi, Tani Tokio

Abstract excerpt

Fission yeast ptr1-1 is one of the mRNA transport mutants that accumulate poly(A)+ RNA in the nuclei at the nonpermissive temperature. We found that the ptr1+ gene encodes a homolog of Saccharomyces cerevisiae Tom1p, a hect type ubiquitin ligase. In ptr1-1, a conserved amino acid in the hect domain of Ptr1p is mutated. The ptr1+ gene is essential for growth and its mutation did not affect nuclear protein export....

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PMID: 15094387
DOI: 10.1016/j.bbrc.2004.03.171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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