Article
-455G/A beta-fibrinogen gene polymorphism, factor V Leiden, prothrombin G20210A mutation and MTHFR C677T, and placental vascular complications.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 2004
Camilleri Raymond S, Peebles Donald, Portmann Carol, Everington Tamara, Cohen Hannah
Abstract excerpt
Hyperfibrinogenaemia is associated with systemic arterial and venous thromboembolism and therefore may contribute to placental vascular disease associated with obstetric complications. The fibrinogen-raising -455G/A beta-fibrinogen gene polymorphism may enhance the physiological increase in fibrinogen levels during pregnancy and thereby predispose to obstetric complications. This retrospective case-control study...
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