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Article

Mycobacteria, genes and the 'hygiene hypothesis'.

Current opinion in allergy and clinical immunology - 1 Feb 2004

Smit Joost J, Folkerts Gert, Nijkamp Frans P

Abstract excerpt

PURPOSE OF REVIEW: The 'hygiene hypothesis' suggests that a relationship exists between improved hygiene and an increase in allergic diseases. As an underlying mechanism for this hypothesis it is proposed that due to the lack of microbial stimulation either a misbalance in T helper type responses or a misbalance in regulatory mechanisms develops. As yet, however, a specific infectious factor responsible for the...

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Source

Identifiers

PMID: 15090921
DOI: 10.1097/00130832-200402000-00012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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