Article
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population.
AIDS (London, England) - 5 Mar 2004
Sagar Manish, Lavreys Ludo, Baeten Jared M, Richardson Barbra A, Mandaliya Kishorchandra, Ndinya-Achola Jeckoniah O, Kreiss Joan K, Overbaugh Julie
Abstract excerpt
BACKGROUND: Our previous studies have shown that the majority of African women were infected with multiple HIV-1 genetic variants, while in the remaining women only a single viral genotype was detected early in infection. Infection with multiple viral variants was associated with higher plasma HIV-1 RNA levels and faster CD4 T-cell decline. METHOD: Socio-behavioral characteristics, use of hormonal contraceptives,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.