Article
Corticosteroid binding globulin: a new target for cortisol-driven obesity.
Molecular endocrinology (Baltimore, Md.) - 1 Jul 2004
Ousova Olga, Guyonnet-Duperat Véronique, Iannuccelli Nathalie, Bidanel Jean-Pierre, Milan Denis, Genêt Carine, Llamas Bastien, Yerle Martine, Gellin Joël, Chardon Patrick, Emptoz-Bonneton Agnès, Pugeat Michel, Mormède Pierre, Moisan Marie-Pierre
Abstract excerpt
We present data suggesting that corticosteroid-binding globulin (CBG) may be the causal gene of a previously identified quantitative trait locus (QTL) associated with cortisol levels, fat, and muscle content in a pig intercross. Because Cbg in human and mouse maps in the region orthologous to the pig region containing this QTL, we considered Cbg as an interesting positional candidate gene because CBG plays a...
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