Article
A novel kinesin-like protein, KIF1Bbeta3 is involved in the movement of lysosomes to the cell periphery in non-neuronal cells.
Traffic (Copenhagen, Denmark) - 1 Mar 2004
Matsushita Masafumi, Tanaka Shingo, Nakamura Norihiro, Inoue Hiroki, Kanazawa Hiroshi
Abstract excerpt
The kinesin superfamily protein, KIF1Bbeta, a splice variant of KIF1B, is involved in the transport of synaptic vesicles in neuronal cells, and is also expressed in various non-neuronal tissues. To elucidate the functions of KIF1Bbeta in non-neuronal cells, we analyzed the intracellular localization of KIF1Bbeta and characterized its isoform expression profile. In COS-7 cells, KIF1B colocalized with lysosomal...
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