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Article

Analyses of p53 expression pattern and BRCA mutations in patients with double primary breast and ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000

Bruchim I, Fishman A, Friedman E, Goldberg I, Chetrit A, Barshack I, Dekel E, Hirsh-Yechezkel G, Modan B, Kopolovic J

Abstract excerpt

OBJECTIVE: To analyze the somatic pattern of p53 expression and BRCA germline mutation status in Israeli patients with both ovarian (OvCa) and breast cancer (BrCa). METHODS: The study group comprised 43 Israeli patients with OvCa, all of whom had previous primary BrCa. p53 immunohistochemistry (IHC) on all available archival tissues and genotyping for the three predominant Jewish germline BRCA1-2 mutations were...

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Share to Cystadenocarcinoma, Serous
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15086724
DOI: 10.1111/j.1048-891X.2004.014208.x

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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