Localization of recognition site between transforming growth factor-beta1 (TGF-beta1) and TGF beta receptor type II: possible implications in breast cancer.

doi:10.1016/j.mehy.2003.11.027

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Localization of recognition site between transforming growth factor-beta1 (TGF-beta1) and TGF beta receptor type II: possible implications in breast cancer.

Medical hypotheses - 1 Jan 2004

Ivanović V, Demajo M, Todorović-Raković N, Nikolić-Vukosavljević D, Nesković-Konstantinović Z, Krtolica K, Veljković V, Prljić J, Dimitrijević B

Abstract excerpt

Although overexpression of TGF-beta1 protein has been demonstrated in advanced breast cancer (BC) patients, as well as in other solid tumours, the molecular mechanism of this process remains obscure. This paper proposes that a genetic/epigenetic alteration might occur in the TGF-beta1 gene, withi...

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Localization of recognition site between transforming growth factor-beta1 (TGF-beta1) and TGF beta receptor type II: possible implications in breast cancer.

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