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Article

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response.

Eukaryotic cell - 1 Apr 2004

Apidianakis Yiorgos, Rahme Laurence G, Heitman Joseph, Ausubel Frederick M, Calderwood Stephen B, Mylonakis Eleftherios

Abstract excerpt

We found that the ingestion of Cryptococcus neoformans by Drosophila melanogaster resulted in the death of the fly but that the ingestion of Saccharomyces cerevisiae or the nonpathogenic Cryptococcus kuetzingii or Cryptococcus laurentii did not. The C. neoformans protein kinase A and RAS signal t...

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Identifiers

PMID: 15075271
DOI: 10.1128/EC.3.2.413-419.2004
PMCID: PMC387633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15075271-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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