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Article

Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum.

Science (New York, N.Y.) - 9 Apr 2004

Kamena Faustin, Spang Anne

Abstract excerpt

Directionality in intracellular trafficking is essential to ensure the correct localization of proteins along the secretory pathway. Here, we found evidence for an active mechanism that prohibited back-fusion of de novo-generated vesicles with their donor compartment. Tip20p is a peripheral membrane protein implicated in consumption of COPI vesicles at the endoplasmic reticulum. However, a specific mutant of...

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Share to alpha-Glucosidases
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Share to Endoplasmic Reticulum

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15073376
DOI: 10.1126/science.1095049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum.PMID 15073376Read ↗

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