Article
The Sec20/Tip20p complex is involved in ER retrieval of dilysine-tagged proteins.
European journal of cell biology - 1 Jun 1997
Cosson P, Schröder-Köhne S, Sweet D S, Démollière C, Hennecke S, Frigerio G, Letourneur F
Abstract excerpt
Sec20p and Tip20p were previously identified as two interacting proteins involved in early steps of the secretory pathway in Saccharomyces cerevisiae. Here we describe a novel temperature-sensitive allele of TIP20 and analyze its phenotype. While sec20 and tip20 mutants exhibited a defect in forward ER-to-Golgi transport at the non-permissive temperature, both were also defective for retrieval of various...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.