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Article

Persistent Aberrations in Circulating DNA Integrity after Radiotherapy Are Associated with Poor Prognosis in Nasopharyngeal Carcinoma Patients

1 Jul 2008

Abstract excerpt

PURPOSE: Aberrations of circulating nucleic acid integrity have been observed in cancer patients. However, the clinical significance of such changes has not been completely elucidated. In this study, we investigated the plasma DNA integrity in nasopharyngeal carcinoma (NPC) patients and its association with patients' survival after radiotherapy. EXPERIMENTAL DESIGN: Plasma DNA integrity was analyzed for 105 NPC...

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PMID: 18593992
DOI: 10.1158/1078-0432.ccr-08-0182

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