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Article

Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population

2 May 2011

Abstract excerpt

BACKGROUND: Undifferentiated nasopharyngeal carcinoma (NPC) is strongly related to Epstein-Barr virus (EBV) infection, allowing aberrant antibodies against EBV and viral DNA load as screening tools in high risk populations. Methylation analysis in the promoter of tumor suppressor genes (TSGs) may serve as a complementary marker for identifying early cases. This study determined methylation status of multiple TSGs...

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PMID: 21535891
DOI: 10.1186/1476-4598-10-48

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