Article
Alu RNA transcripts in human embryonal carcinoma cells. Model of post-transcriptional selection of master sequences.
Journal of molecular biology - 5 Aug 1992
Sinnett D, Richer C, Deragon J M, Labuda D
Abstract excerpt
Alu master sequences colonized the human genome using RNA as amplification intermediate. To understand this phenomenon better we isolated and analyzed Alu RNA from NTera2D1 pluripotential cells. Northern hybridization, primer extension, cDNA cloning and sequencing data are congruent and demonstra...
Topics
- Base Sequence
- Blotting, Northern
- Cell Line
- Cell Nucleus
- Cloning, Molecular
- Cytoplasm
- Gene Library
- Genetic Variation
- Genome, Human
- Humans
- Models, Genetic
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Plasmids
- Polymerase Chain Reaction
- RNA Polymerase II
- RNA Processing, Post-Transcriptional
- RNA, Neoplasm
