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Article

Germline mutations in BRCA2: shared genetic susceptibility to breast cancer, early onset leukemia, and Fanconi anemia.

Blood - 15 Apr 2004

Wagner John E, Tolar Jakub, Levran Orna, Scholl Thomas, Deffenbaugh Amie, Satagopan Jaya, Ben-Porat Leah, Mah Katherine, Batish Sat Dev, Kutler David I, MacMillan Margaret L, Hanenberg Helmut, Auerbach Arleen D

Abstract excerpt

The breast cancer susceptibility gene BRCA2 has recently been identified as identical to the Fanconi anemia (FA) gene FANCD1. Here we expand the clinical implications of this discovery. Notably, we identified 6 children in 5 kindreds exhibiting the co-occurrence of BRCA2 mutations, FA, and early...

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Source

Identifiers

PMID: 15070707
DOI: 10.1182/blood-2003-09-3138

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15070707-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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