Article
Polymorphisms of the endothelial nitric oxide synthase gene - no consistent association with myocardial infarction in the ECTIM study.
European journal of clinical investigation - 1 Apr 1999
Poirier O, Mao C, Mallet C, Nicaud V, Herrmann S M, Evans A, Ruidavets J B, Arveiler D, Luc G, Tiret L, Soubrier F, Cambien F
Abstract excerpt
BACKGROUND: Our aim in the present study was to determine whether endothelial NO synthase gene (ecNOS) polymorphisms are associated with myocardial infarction (MI). METHODS: Forty chromosomes from patients with MI were screened for polymorphisms of the ecNOS gene using polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis and sequencing. Ten polymorphisms were detected: three in...
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