Article
A monoclonal antibody specific to the HA2 glycoprotein of influenza A virus hemagglutinin that inhibits its fusion activity reduces replication of the virus.
Acta virologica - 1 Jan 2003
Varecková E, Wharton S A, Mucha V, Gocník M, Kostolanský F
Abstract excerpt
Monoclonal antibody (MAb) CF2, which binds to the fusion peptide of influenza A virus hemagglutinin (HA) (amino acids (aa) 1-35 of the N-terminus of the light chain of HA), inhibited the fusion activity of HA. This MAb preferentially bound to pH 5-treated virus (with conformationally altered HA)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
