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Article

Active succinate dehydrogenase (SDH) and lack of SDHD mutations in sporadic paragangliomas.

Anticancer research - 1 Jan 2000

Braun Simone, Riemann Kathrin, Kupka Susan, Leistenschneider Peter, Sotlar Karl, Schmid Heide, Blin Nikolaus

Abstract excerpt

BACKGROUND: Paragangliomas are benign, slow-growing tumours of the head and neck region. The candidate gene for familial and some sporadic paragangliomas, SDHD (succinate dehydrogenase, subunit D), has been mapped to the PGL1 locus in 11q23.3. MATERIALS AND METHODS: Normal and tumour DNA of 17 patients with sporadic paragangliomas were analysed by sequencing (SDHD, SDHB and SDHC genes), fluorescence in situ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16080530

Genes

SDHD
SDHB
SDHC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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