Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of the SDHD gene locus in midgut carcinoids, Merkel cell carcinomas, pheochromocytomas, and abdominal paragangliomas.

Genes, chromosomes & cancer - 1 Jul 2002

Kytölä Soili, Nord Brita, Elder Elisabeth Edström, Carling Tobias, Kjellman Magnus, Cedermark Björn, Juhlin Claes, Höög Anders, Isola Jorma, Larsson Catharina

Abstract excerpt

Several types of endocrine tumors show frequent somatic deletions of the distal part of chromosome arm 11q, where the tumor-suppressor gene SDHD (succinate-ubiquinone oxidoreductase subunit D), constitutionally mutated in paragangliomas of the head and neck, is located. In this study, we screened 18 midgut carcinoids, 7 Merkel cell carcinomas, 46 adrenal pheochromocytomas (37 sporadic and 9 familial), and 7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abdominal Neoplasms
Share to Adrenal Gland Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoid Tumor

Share to Carcinoma, Merkel Cell

Share to Electron Transport Complex II

Share to Intestinal Neoplasms

Share to Paraganglioma

Share to Pheochromocytoma

Source

Identifiers

PMID: 12007193
DOI: 10.1002/gcc.10081

Genes

SDHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of the SDHD gene locus in midgut carcinoids, Merkel cell carcinomas, pheochromocytomas, and abdominal paragangliomas.PMID 12007193Read ↗

Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum.Semantic proximity Read ↗

Distinct Clinical Features of Paraganglioma Syndromes Associated With <EMPH TYPE="ITAL">SDHB</EMPH> and <EMPH TYPE="ITAL">SDHD</EMPH> Gene MutationsSemantic proximity Read ↗

Succinate Dehydrogenase-deficient TumorsSemantic proximity Read ↗

Prevalence and spectrum of SDHx mutations in pheochromocytoma and paraganglioma in patients from Belgium: an update.Semantic proximity Read ↗

Mutations of the SDHB and SDHD genes.Semantic proximity Read ↗

SDH mutations in tumorigenesis and inherited endocrine tumours: lesson from the phaeochromocytoma-paraganglioma syndromes.Semantic proximity Read ↗

Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD.Semantic proximity Read ↗

Loss of maternal chromosome 11 is a signature event in SDHAF2, SDHD, and VHL-related paragangliomas, but less significant in SDHB-related paragangliomas.Semantic proximity Read ↗

The SDHD:p.H102R Variant Is Frequent in Russian Patients with Head and Neck Paragangliomas and Associated with Loss of 11p15.5 Region and Hypermethylation of H19-DMR.Semantic proximity Read ↗

Clinical Characteristics of Pheochromocytoma Patients With Germline Mutations in SDHDSemantic proximity Read ↗

Reduced expression and loss of heterozygosity of the SDHD gene in colorectal and gastric cancerSemantic proximity Read ↗

Mutation analysis of SDHB and SDHC: novel germline mutations in sporadic head and neck paraganglioma and familial paraganglioma and/or pheochromocytomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.