Article
The T-stem determines the cytosolic or mitochondrial localization of trypanosomal tRNAsMet.
Molecular biology of the cell - 1 Jun 2004
Crausaz Esseiva Anne, Maréchal-Drouard Laurence, Cosset Anne, Schneider André
Abstract excerpt
The mitochondrion of Trypanosoma brucei lacks tRNA genes. Organellar translation therefore depends on import of cytosolic, nucleus-encoded tRNAs. Except for the cytosol-specific initiator tRNA(Met), all trypanosomal tRNAs function in both the cytosol and the mitochondrion. The initiator tRNA(Met) is closely related to the imported elongator tRNA(Met). Thus, the distinct localization of the two tRNAs(Met) must be...
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