Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genes

1 Apr 2004

Abstract excerpt

BACKGROUND: Antibody fragments selected from large combinatorial libraries have numerous applications in diagnosis and therapy. Most existing antibody repertoires are derived from human immunoglobulin genes. Genes from other species can, however, also be used. Because of the way in which gene conversion introduces diversity, the naïve antibody repertoire of the chicken can easily be accessed using only two sets...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal health and immunology
Share to Bacteriophages and microbial interactions
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15059288
DOI: 10.1186/1472-6750-4-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genesPMID 15059288Read ↗

Reconciling the Structural Attributes of Avian AntibodiesSemantic proximity Read ↗

A compact phage display human scFv library for selection of antibodies to a wide variety of antigensSemantic proximity Read ↗

Selection and Application of Human Single Chain Fv Antibody Fragments from a Semi-synthetic Phage Antibody Display Library with Designed CDR3 RegionsSemantic proximity Read ↗

Selection of specific phage-display antibodies using libraries derived from chicken immunoglobulin genesSemantic proximity Read ↗

Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage displaySemantic proximity Read ↗

Introduction to Antibody Engineering and Phage DisplaySemantic proximity Read ↗

Chicken monoclonal antibody isolated by a phage display systemSemantic proximity Read ↗

Creation of the large and highly functional synthetic repertoire of human VH and Vκ domain antibodies.Semantic proximity Read ↗

The role of phage display in therapeutic antibody discoverySemantic proximity Read ↗

A multi-Fc-species system for recombinant antibody productionSemantic proximity Read ↗

Construction of naïve camelids VHH repertoire in phage display-based librarySemantic proximity Read ↗

Heavy chain-only antibodies with a stabilized human VH in transgenic chickens for therapeutic antibody discoverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.