Article
New variants in the apolipoprotein AV gene in individuals with extreme triglyceride levels.
Physiological research - 1 Jan 2004
Hubácek J A, Adámková V, Ceska R, Poledne R, Horínek A, Vráblík M
Abstract excerpt
Animal studies (on transgenic and knock-out mice) and human association analysis assessed the importance of APOAV gene for plasma triglyceride determination. New APOAV missense variants (Val153 --> Met and Cys185 --> Gly) have been detected recently. We have analyzed these variants in 83 unrelated patients with extreme lipid parameters (triglycerides of 20.4+/-2.8 mmol/l and total cholesterol of 10.4+/-3.7...
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