Article
The association between paired basic amino acid cleaving enzyme 4 gene haplotype and diastolic blood pressure.
Chinese medical journal - 1 Mar 2004
Li Jian-ping, Wang Xiao-bin, Chen Chang-zhong, Xu Xin, Hong Xue-mei, Xu Xi-ping, Gao Wei, Huo Yong
Abstract excerpt
BACKGROUND: In a previously identified locus linked to hypertension on chromosome 15q, we identified three blood pressure candidate genes: insulin-like growth factor 1 receptor gene (IGF1R), myocyte specific enhancer factor 2A gene (MEF2A), and paired basic amino acid cleaving enzyme 4 gene (PACE4). In this study, we tested their associations with hypertension using haplotype analysis. METHODS: A total of 288...
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