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Article

Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism.

European journal of biochemistry - 1 Apr 2004

Amichot Marcel, Tarès Sophie, Brun-Barale Alexandra, Arthaud Laury, Bride Jean-Marc, Bergé Jean-Baptiste

Abstract excerpt

Three point mutations R335S, L336V and V476L, distinguish the sequence of a cytochrome P450 CYP6A2 variant assumed to be responsible for 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT) resistance in the RDDT(R) strain of Drosophila melanogaster. To determine the impact of each mutation on t...

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Identifiers

PMID: 15030474
DOI: 10.1111/j.1432-1033.2004.04025.x

Genes

DDT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15030474-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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