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Article

Linkage of myostatin pathway genes with knee strength in humans

23 Mar 2004

Abstract excerpt

This study was the first to explore the potential role of the myostatin (GDF8) pathway in relation to muscle strength and estimated muscle cross-sectional area in humans using linkage analysis with a candidate gene approach. In young male sibs (n = 329) 11 polymorphic markers in or near 10 candidate genes from the myostatin pathway were genotyped. Muscle mass was estimated by anthropometric measurements, and...

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PMID: 15026560
DOI: 10.1152/physiolgenomics.00224.2003

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