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Article

Quantitative trait loci for human muscle strength: linkage analysis of myostatin pathway genes.

Physiological genomics - 11 Aug 2005

Huygens W, Thomis M A I, Peeters M W, Aerssens J, Vlietinck R, Beunen G P

Abstract excerpt

This study reports the results of a multipoint linkage study that aims to unravel the genetic basis of muscle strength and muscle mass in humans. Myostatin (GDF8) is known to be a strong inhibitor of muscle growth in animals. However, studies examining human myostatin polymorphisms are rare and are limited to the GDF8 gene itself. Here, the contribution to isometric and concentric knee strength of nine key...

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Identifiers

PMID: 15914581
DOI: 10.1152/physiolgenomics.00010.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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