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Article

Characterization of the t(14;18) <b> <i>BCL2-IGH</i> </b> Translocation in Farmers Occupationally Exposed to Pesticides

15 Mar 2004

Abstract excerpt

Increasing incidence of non-Hodgkin's lymphoma have been associated repeatedly with farming occupation and particular attention focused on the role of pesticide exposure to potentially explain part of this trend. A genetic hallmark of non-Hodgkin's lymphoma is the presence of recurrent chromosomal translocations involving the immunoglobulin heavy chain gene. Of these, the t(14;18), which deregulates BCL2...

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PMID: 15026372
DOI: 10.1158/0008-5472.can-03-3604

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