Article
AtPARN is an essential poly(A) ribonuclease in Arabidopsis.
Gene - 17 Mar 2004
Chiba Yukako, Johnson Mark A, Lidder Preetmoninder, Vogel Jonathan T, van Erp Harrie, Green Pamela J
Abstract excerpt
Deadenylation is the first and rate-limiting step in the degradation of many mRNAs in a wide-range of organisms from yeast to higher eukaryotes. It can also play a regulatory role in early development. In this study, we examined the Arabidopsis homolog of poly(A) ribonuclease (PARN), a deadenylase first identified in mammals and absent from yeast. Consistent with the conservation of domains and residues important...
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