Article
NTR1 is required for transcription elongation checkpoints at alternative exons in Arabidopsis.
The EMBO journal - 12 Feb 2015
Dolata Jakub, Guo Yanwu, Kołowerzo Agnieszka, Smoliński Dariusz, Brzyżek Grzegorz, Jarmołowski Artur, Świeżewski Szymon
Abstract excerpt
The interconnection between transcription and splicing is a subject of intense study. We report that Arabidopsis homologue of spliceosome disassembly factor NTR1 is required for correct expression and splicing of DOG1, a regulator of seed dormancy. Global splicing analysis in atntr1 mutants revealed a bias for downstream 5' and 3' splice site selection and an enhanced rate of exon skipping. A local reduction in...
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