Article
Plasmodium falciparum: distribution of msp2 genotypes among symptomatic and asymptomatic individuals from the Wosera region of Papua New Guinea.
Experimental parasitology - 1 Jan 2000
Cortés Alfred, Mellombo Mata, Benet Ariadna, Lorry Kerry, Rare Lawrence, Reeder John C
Abstract excerpt
The merozoite surface protein 2 (MSP2) is a leading asexual-stage malaria vaccine candidate that has already proven to have an effect in phase I/IIb vaccine trials, where it was tested in combination with other antigens. Alleles of msp2 fall within two major allelic families, 3D7 and FC27. We analyzed the msp2 genotype in 306 asymptomatic and 63 symptomatic infections from the Wosera region of Papua New Guinea....
Topics
- Adolescent
- Adult
- Age Distribution
- Animals
- Antigens, Protozoan
- Child
- Child, Preschool
- Cross-Sectional Studies
- Gene Frequency
- Genetic Markers
- Genotype