Article
Genetic diversity of Plasmodium falciparum isolates from naturally infected children in north-central Nigeria using the merozoite surface protein-2 as molecular marker.
Asian Pacific journal of tropical medicine - 1 Aug 2013
Oyedeji Segun Isaac, Awobode Henrietta Oluwatoyin, Anumudu Chiaka, Kun Jürgen
Abstract excerpt
OBJECTIVE: To characterize the genetic diversity of Plasmodium falciparum (P. falciparum) field isolates in children from Lafia, North-central Nigeria, using the highly polymorphic P. falciparum merozoite surface protein 2 (MSP-2) gene as molecular marker. METHODS: Three hundred and twenty children were enrolled into the study between 2005 and 2006. These included 140 children who presented with uncomplicated...
Topics
- Animals
- Antigens, Protozoan
- Child
- Child, Preschool
- DNA, Protozoan
- Female
- Genetic Variation
- Genotype
- Humans
- Infant
- Malaria, Falciparum
- Male
- Nigeria
- Plasmodium falciparum
- Polymerase Chain Reaction