Article
Enhanced expression of the P2X4 receptor in Duchenne muscular dystrophy correlates with macrophage invasion.
Neurobiology of disease - 1 Mar 2004
Yeung Davy, Kharidia Riddhi, Brown Susan C, Górecki Dariusz C
Abstract excerpt
Following molecular and immunohistochemical analysis of the purinergic P2X4 receptor subunit in dystrophin-deficient muscle we have identified a distinct subpopulation of P2X4-positive cells infiltrating the dystrophic fibres. These cells were absent from normal muscle and rarely present in the dystrophic muscle taken before and after the onset of degeneration. We have identified these P2X4-positive cells as...
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