Article
EGFR signaling to p120-catenin through phosphorylation at Y228.
Journal of cell science - 15 Mar 2004
Mariner Deborah J, Davis Michael A, Reynolds Albert B
Abstract excerpt
Epidermal growth factor receptor (EGFR) signals to p120(ctn) (p120), implying a role for EGFR in modulating cell-cell adhesion in epithelial tissues. p120 controls cadherin turnover, and may have other roles that modulate cadherin adhesiveness. To clarify the role for EGFR and other tyrosine kinases in regulating p120 function, we have generated and characterized a new phosphospecific antibody to p120 Y228, as...
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