Article
A gene essential to brain growth and development maps to the distal arm of rat chromosome 12.
Neuroscience letters - 17 Jul 1998
Cogswell C A, Sarkisian M R, Leung V, Patel R, D'Mello S R, LoTurco J J
Abstract excerpt
A recently discovered, spontaneous, autosomal recessive mutation in rats, flathead (fh), results in greatly reduced brain growth beginning in late fetal development. In this study we have mapped the fh mutation by determining the pattern of segregation of polymorphic microsatellite markers with respect to fh in 51 affected F2 offspring from a single interstrain intercross. Two markers on chromosome 12, D12Rat80...
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