Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Campylobacter jejuni infection of differentiated THP-1 macrophages results in interleukin 1 beta release and caspase-1-independent apoptosis.

Microbiology (Reading, England) - 1 Mar 2004

Siegesmund Amy M, Konkel Michael E, Klena John D, Mixter Philip F

Abstract excerpt

Apoptosis induction of host macrophages has emerged as a common virulence mechanism among bacterial pathogens. Infection with Campylobacter jejuni is a leading cause of gastroenteritis worldwide and is characterized by an acute inflammatory response in the small intestine. The authors used the human monocytic cell line THP-1 to examine apoptosis induction and pro-inflammatory cytokine production during C. jejuni...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Campylobacter Infections
Share to Caspase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspase 9

Share to Caspase Inhibitors

Share to Caspases

Share to Cysteine Proteinase Inhibitors

Share to Gastroenteritis

Share to Interleukin-1

Source

Identifiers

PMID: 14993305
DOI: 10.1099/mic.0.26466-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Campylobacter jejuni infection of differentiated THP-1 macrophages results in interleukin 1 beta release and caspase-1-independent apoptosis.PMID 14993305Read ↗

Strain-dependent induction of epithelial cell oncosis by Campylobacter jejuni is correlated with invasion ability and is independent of cytolethal distending toxin.Semantic proximity Read ↗

Campylobacter jejuni cell lysates differently target mitochondria and lysosomes on HeLa cells.Semantic proximity Read ↗

Biphasic Modulation of Apoptotic Pathways in <i>Cryptosporidium parvum</i> -Infected Human Intestinal Epithelial CellsSemantic proximity Read ↗

Helicobacter pylori induces apoptosis of macrophages in association with alterations in the mitochondrial pathway.Semantic proximity Read ↗

Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infectionSemantic proximity Read ↗

Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitisSemantic proximity Read ↗

Derepression of Salmonella pathogenicity island 1 genes within macrophages leads to rapid apoptosis via caspase-1- and caspase-3-dependent pathways.Semantic proximity Read ↗

Helicobacter pylori Induces Apoptosis of Human Monocytes but Not Monocyte-Derived Dendritic Cells: Role of the cag Pathogenicity IslandSemantic proximity Read ↗

Helicobacter pylori lipopolysaccharide from type I, but not type II strains, stimulates apoptosis of cultured gastric mucosal cells.Semantic proximity Read ↗

Growth phase-regulated induction of Salmonella-induced macrophage apoptosis correlates with transient expression of SPI-1 genes.Semantic proximity Read ↗

Intestinal Epithelial Cell Apoptosis following<i>Cryptosporidium parvum</i>InfectionSemantic proximity Read ↗

Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.